Navigating the world of skincare can be overwhelming. With countless options on the market, it's hard to separate what's effective from what's just hype.
That’s where our editors can help. We’ve identified two of the most popular products designed to address advanced anti-aging and skin rejuvenation with growth factors: TNS Advanced+ Serum by SkinMedica and the Droplette Microinfuser Growth Factors Concentrate Set.
Growth factors are proteins naturally produced by the body that stimulate the growth and repair of skin cells, playing a crucial role in maintaining youthful, healthy skin by activating stem cells and replacing aging cells with new, revitalized ones.
Both brands are at the forefront of skincare innovation, promising significant improvements in skin texture, firmness, and overall radiance. But which do we recommend? See our breakdown below:
Key Similarities
- Growth Factors: Both products focus on growth factors for skin repair and collagen stimulation.
- Anti-Aging: Each product targets fine lines, wrinkles, and skin firmness.
- Clinical Testing: Both have been clinically tested and proven effective.
Key Differences
- Droplette uses a micro-infusion device for deeper ingredient penetration, while TNS Advanced+ Serum is applied topically which is a limiting factor in efficacy, as growth factors are too large to cross the skin barrier when applied in serum or cream format.
- Droplette includes stem cell-derived conditioned media with higher concentrations of growth factors like EGF and TGF-Beta, sourced from a biotechnology company specializing in stem cell therapeutics. In contrast, TNS Advanced+ Serum uses natural growth factors and peptides, but at lower concentration levels.
- Droplette is clinically validated, NASA-backed, NIH award-winning, and one of Time Magazines's best inventions. TNS Advanced+ Serum is an Allure’s Best of Beauty award winner.
- Droplette’s formulation is kept cold to preserve efficacy, as growth factors are unstable at room temperature. TNS Advanced+ Serum is formulated for room temperature storage which may affect the stability and potency of its active ingredients.
Droplette's Growth Factors Concentrate Microinfuser Set Overview
The Droplette Growth Factors Set is a breakthrough in skincare technology, revolutionizing how we treat our skin with potent, premium ingredients. At the core of this product is the Droplette Microinfuser device— an innovative micro-infusion system that transforms skincare application by delivering active ingredients 20 times deeper into the skin via its patented micromist compared to traditional topicals.
The Droplette Microinfuser Systemdelivers cutting-edge growth factor ingredients that work to promote youthful, radiant skin along with other powerful anti-aging ingredients such as peptides and amino acids.. Growth factors are too large to enter the skin topically because of their size. Droplette’s Microinfuser overcomes the limitation and successfully delivers them into the skin.
The Droplette Growth Factors Set revolutionizes anti-aging skincare by delivering clinical-grade results at home—results that were only possible with dermatology clinics in the past.
TNS Advanced+ Serum by SkinMedica Overview
The TNS Advanced+ Serum by SkinMedica is a dual-chamber serum that blends advanced growth factors with peptides to target aging skin. Designed for twice-daily application, it works to reduce fine lines, wrinkles, and improve skin tone and texture. This serum is known for its ability to rejuvenate the skin by supporting collagen production and cell renewal.
Unlike Droplette’s formulation, which is kept cold to preserve efficacy, TNS Advanced+ Serum is formulated for room-temperature storage, which may affect the stability and efficacy of its active ingredients.
While results can take weeks to become noticeable, the TNS Advanced+ Serum is a reliable choice for those seeking a more traditional, straightforward solution to visible signs of aging. However, it doesn't offer the deep, 20X deeper penetration or personalized, tech-driven approach that the Droplette Microinfusion Delivery System provides.
Because TNS Advanced+ Serum is applied topically, it doesn’t allow the core growth factor ingredients to cross the skin barrier effectively, limiting its potential impact. TNS Advanced+ Serum uses natural growth factors and peptides but does not reach the same concentration levels as Droplette, which includes stem cell-derived conditioned media with higher concentrations of growth factors like EGF and TGF-Beta.
Our Verdict
Both the Droplette Growth Factors Set and TNS Advanced+ Serum by SkinMedica have anti-aging benefits, but the Droplette system stands out for several reasons.
The Droplette Growth Factors Setis $499 with their subscription, a higher initial investment than $295 for the TNS Advanced+ Serum. But this includes a cutting-edge device that delivers ingredients 20X deeper into the skin than traditional topicals like the TNS Advanced+ Serum. This deeper penetration leads to faster, more noticeable results, making the Droplette Growth Factors Set worth every penny.
Not to mention the quality of the growth factors Droplette uses are pharmaceutical-grade and fully traceable. Plus, Droplette’s Growth Factors are kept cold to ensure the highest quality and potency, giving you results that rival clinical treatments from the comfort of home.
If you’re looking for a smart, long-term investment in your skin's health and vitality, we highly recommend the Droplette Growth Factors Set.